BioSync\u2122 Precision Yeast Synthesis
The Gold Standard for Infant Nutrition & Gut Health.
Endotoxin-free, E. coli-free Human Milk Oligosaccharides at 99.9% purity. First FDA GRAS globally for LNTr II. Manufactured for Morika Bio.
BioSync™ 3rd-Gen Yeast Synthesis
Endotoxin-Free & E. coli-Free
Legacy HMO production relies on engineered E. coli expression systems, which carry inherent endotoxin (LPS) risk. Our BioSync™ platform uses a food-grade yeast chassis to produce pharmaceutical-grade HMOs with zero endotoxin contamination -- a critical safety advantage for infant nutrition that older bacterial systems cannot match.
Zero Endotoxin Risk
Yeast cells do not produce lipopolysaccharide (LPS) endotoxins, eliminating the most critical contamination vector in infant-grade ingredients. No costly endotoxin removal steps required.
E. coli-Free Production Chain
Complete elimination of gram-negative bacteria from the production chain. No risk of pathogenic contamination in final product.
99.9% Purity | pH 6.7 | Moisture < 0.2%
Standardized physical properties across all HMO variants. Verified by independent ISO 17025 accredited laboratories.
Download Our Independent GRAS Conclusion Report
Distributed by Morika Bio | Human Milk Oligosaccharides (HMOs)
Platform Comparison
BioSync™ Yeast vs. Legacy E. coli Systems
A direct comparison of our 3rd-generation yeast synthesis platform against traditional bacterial expression systems used by most competitors.
Data represents typical production parameters. Manufactured for Morika Bio.
Product Portfolio
Key HMO Variants
Each variant is produced under our BioSync™ platform and verified through Morika Bio Global Quality Unit.
C₁₈H₃₂O₁₄
2'-Fucosyllactose (2'-FL)
Most abundant HMO in human milk
C₂₆H₄₅NO₂₀
Lacto-N-neotetraose (LNnT)
Key bifidogenic factor
C₂₀H₃₇NO₁₅
Lacto-N-triose II (LNTr II)
First FDA GRAS globally via BioSync™
Technical Data
Typical Certificate of Analysis Parameters
Standardized COA parameters across the HMO portfolio. Full batch-specific COAs available upon request through The Vault.
HMO COA Parameters (Standardized)
| Parameter | Specification |
|---|---|
| Purity (HPLC) | 99.9% |
| pH (1% solution) | 6.7 Neutral |
| Moisture | < 0.2% |
| Ash | < 0.1% |
| Endotoxin (LPS) | Zero Risk (Yeast Platform) |
| Residual Solvents | Meets ICH Q3C |
| Heavy Metals (total) | < 5 ppm |
| Microbial Count | < 100 CFU/g |
| E. coli | Absent |
| Salmonella | Absent / 25g |
Application Areas
Designed for Critical Applications
Infant Formula
Gold-standard HMO supplementation for premium infant formula. Supports gut microbiome colonization and immune development. Endotoxin-free for maximum safety.
Adult Gut Health
Prebiotic supplementation for adult digestive wellness. Promotes beneficial Bifidobacterium growth and SCFA production.
Clinical Nutrition
Medical-grade HMOs for clinical nutrition products targeting immune modulation and gut barrier integrity.
Regulatory & Compliance
All certifications verified through Morika Bio Global Quality Unit. Manufactured for Morika Bio.