Morika Bio Technical & Quality Team

Regulatory & Compliance

Navigating global regulatory frameworks across the US, EU, and Asia-Pacific.

Regulatory Landscape

Multi-Region Market Access

Morika Bio technical and quality teams support documentation across major regulatory jurisdictions. Every product is supported with region-specific documentation to support target-market review.

United States

US

FDA GRAS Notified

HMOs (2'-FL, LNT, LNTr II)

FDA GRAS No-Objection

LNTr II

Regulatory status confirmed by intended use

Salidroside

DSHEA-compliant NDI

Manufacturing

cGMP 21 CFR Part 111

All HMO variants carry FDA GRAS no-objection letters. Yeast-based precision fermentation eliminates endotoxin concerns flagged in E. coli-derived alternatives.

European Union

EU

Novel Food Authorized

HMOs (2'-FL, LNT)

EU Novel Food Reg. 2015/2283

LNTr II

Dossier under review

Salidroside

Existing food supplement

Manufacturing

FSSC 22000 Certified

FSSC 22000 and Novel Food documentation is supplied according to the applicable product, facility, and target market.

Asia-Pacific

APAC

Multi-Market Access

China (SAMR)

New food ingredient filing

Japan (MHLW)

Foods with Function Claims

South Korea (MFDS)

Health functional food

ASEAN

Harmonized food supplement

Halal Certification

Available for applicable product lines

Our Shanghai APAC headquarters provides on-ground regulatory support for China SAMR filings and regional market access across key Asian markets.

Certifications

Comprehensive Quality Assurance

Certification copies and scope details are reviewed before release and maintained with continuous audit programs.

FDA GRAS

No-objection letters for all HMO variants. First globally for LNTr II.

FSSC 22000

Food safety management certification for manufacturing facilities.

FDA GRAS

GRAS notification or self-affirmed safety dossiers for applicable US food-ingredient categories.

Halal Support

Certification copies and scope details for applicable product lines.

GMP Compliant

Current Good Manufacturing Practice for dietary supplements.

EU Novel Food

Regulation 2015/2283 authorization for HMO variants.

CITES Compliant

Precision fermentation eliminates need for wild plant harvesting.

Heavy-Metal Tested

ICP-MS verified: Pb, As, Cd, Hg below detection limits.

Regulatory Advantage

Precision Fermentation Eliminates E. coli Regulatory Burden

Legacy E. coli-based fermentation systems require extensive endotoxin testing, additional purification steps, and heightened regulatory scrutiny across all jurisdictions. 3rd-Gen Precision Yeast Synthesis is inherently designed to reduce the endotoxin-management burden associated with bacterial hosts.

Endotoxin Testing

Not Required
Mandatory

Additional Purification

Not Required
2-3 Extra Steps

Regulatory Timeline

Standard
Extended Review

Partner Support

Regulatory Documentation on Demand

Morika Bio technical and quality teams provide applicable regulatory support packages tailored to your target market.

FDA GRAS No-Objection Letters

EU Novel Food Application Dossiers

Toxicological Safety Assessments

Stability Testing Data (ICH Zones I-IV)

Certificate of Analysis (batch-specific)

Allergen & GMO Status Declarations

Country-Specific Import Documentation

Halal & Kosher Certification Copies

Regulatory & Compliance | Morika Bio